Cold sore virus linked to Alzheimer’s disease

A recent paper, published in the Journal of Pathology, by researchers at the University of Manchester, has found a link between cold sores and Alzheimer’s disease. The authors suggest that the virus that causes cold sores (herpes simplex virus type 1) is a major cause of amyloid plaques and is probably a significant factor in the development of Alzheimer’s disease. They suggest the use of antiviral agents to treat the disease, and possibly of vaccination to prevent it.  


MA Wozniak, AP Mee and RF Itzhaki. Herpes simplex virus type I DNA is located within Alzheimer’s disease amyloid plaques. The Journal of Pathology, 2008; 217 (1): 131-138.

Further information:

Science Daily